KOLES is a pure herbal remedy for lowering high cholesterol and triglycerides. It is especially formulated from pure herbs which have scientifically proven effective in lowering elevated plasma lipids such cholesterol and triglycerides. It also improves digestion and is tonic for nerves and muscles.

Ingredients:

• Emblica officinalis

• Terminalia belerica

• Piper longum

• Orchis mascula

• Plumbago zeylanica

• Cinnamomum officinalis

• Aristolochia rotunda

• Zingiber officinale

• Matricaria chamomile

Indications:

Dyslipidemia (High LDL-C, low HDL-C and/or High triglycerides).

Dosage:

Dosage: 1-2 capsules daily after meal, not recommended for children under 12 years age.

Side Effects:

No side effect has been reported at recommended dosage.

Presentation:

Bottle of 30 Capsules.

Medical Research on Koles Formulation (POL-10)

Recent research studies on Koles (POL-10) reported in Vascular Pharmacology¹ have shown that it significantly reduced blood pressure, triglyceride levels and improved atherosclerosis in spontaneously hypertensive rats. In another model of high fat diet-induced hypercholesterolemia Koles significantly reduced serum cholesterol and atherogenic indices. The possible mode(s) of action included, calcium channel blockade, inhibition of absorption and synthesis of lipid biosynsthesis possibly by inhibition of HMG-CoA and antioxidant properties.

A copy of published paper is attached for ready reference.

1Aziz,
N., Mehmood, M.H.,
Mandukhal, S.R., Bashir, S., Raoof, S., Gilani, A.H. (2009).
Antihypertensive, antioxidant, antidyslipidemic and endothelial
modulating activities of a polyherbal formulation (POL-10). Vascular
Pharmacology 50:
57-64 .